You are in the College of Science and Liberal ArtsCollege of Science and Liberal Arts

Department of Chemistry and Environmental Science

Huang, Haidong

Contact Info
Title:
Email: haidong.huang@njit.edu
Office: 370 Tiernan Hall
Phone: 973-596-3576
Dept: Chemistry and Environmental Science
Webpage:

Academic Interests: bioorganic chemistry, nucleotides

About Me

Education

  • Ph.D 2006, State University of New York at Stony Brook
  • BS 2000, Peking University, China

Courses I Teach

ORGANIC CHEMISTRY II
ORGANIC CHEMISTRY II LAB
MASTERS PROJECT
MASTERS THESIS
MASTERS THESIS
DOCTORAL DISSERTATION
DOCTORAL DISSERTATION

1.    Zixing Zhuang, Rui Pan, Qian Zhang, Haidong Huang, Molecular Recognition of Pyrimidines by Triplex DNA Receptors. Bioorg. Med. Chem. Lett. 2015, 25, 1520-1524.

2.    Haidong Huang, Peter C. Tlatelpa. Tuning the Selectivity of Triplex DNA Receptors. Chem. Commun. 2015, 51, 5337-5339.

3.    Peter C. Tlatelpa, Haidong Huang. Stability of Pyrimidine N-glycosydic Bonds in the Presence of Lawesson’s Reagents: Revisit of 2-Thiolation of Pyrimidine Nucleosides. Tetrahedron Lett. 2014, 55, 4780-4784.

4.    Jagruti Rana, Haidong Huang, Actions of the Klenow Fragment of DNA Polymerase I and Some DNA Glycosylases on Chemically Stable Analogues of N7-methyl-2’-deoxyguanosine. Bioorg. Med. Chem. 2013, 21, 6886-6892.

5.    Qian Zhang, Yiqi Wang, Xianyang Meng, Rik Dhar, Haidong Huang, Triple-stranded DNA Containing 8-Oxo-7,8-dihydro-2’-deoxyguanosine: Implication in the Design of Selective 8-Oxo-7,8-dihydroguanine Aptamer Sensors. Anal. Chem. 2013, 85, 201-207.

6.    Sejal Patel, Jagruti Rana, Jyoti Roy, Haidong Huang, Cleavage of Pyrene-stabilized RNA Bulge Loop by Cyclohexane-1,2-diamine. Chem. Cen. J. 2012, 6:3.

7.    Jyoti Roy, Payal Chirania, Sanniv Ganguly, Haidong Huang, A DNA Aptamer Sensor for 8-Oxo-7,8-dihydroguanine. Bioorg. Med. Chem. Lett., 2012, 22, 863-867.

8.    Mayurbhai Patel, Avishek Dutta, Haidong Huang, A Selective Adenosine Sensor Derived from a Triplex DNA Aptamer. Anal. Bioanal. Chem. 2011, 400, 3035-3040.

9.    Haidong Huang, Shuhei Imoto, Marc M. Greenberg, The Mutagenicity of Thymine Glycol in E. coli Is Increased When It Is Part of a Tandem Lesion. Biochemistry 2009, 48, 7833-7841.

10.  Haidong Huang, James T. Stivers, Marc M. Greenberg, Competitive Inhibition of Uracil DNA Glycosylase by a Modified Nucleotide Whose Triphosphate Is a Substrate for DNA Polymerase. J. Am. Chem. Soc. 2009, 131, 1344-1345.

11.  Haidong Huang, Marc M. Greenberg, Hydrogen Bonding Contributes to the Selectivity of Nucleotide Incorporation Opposite an Oxidized Abasic Lesion by DNA Polymerases. J. Am. Chem. Soc. 2008, 130, 6080-6081.

12.  Haidong Huang, Marc M. Greenberg, Synthesis and Analysis of Oligonucleotides Containing Abasic Site Analogues. J. Org. Chem. 2008, 73, 2695-2703.

13.  Haidong Huang, Dale G. Drueckhammer, A Modular Molecular Tweezer Designed Using CAVEAT, Chem. Commun. 2006, 2995-2997.

14.  Haidong Huang, Dale G. Drueckhammer, A Computer-Designed Macrocyclic Zinc Receptor, Chem. Commun. 2005, 5196-5198.

15.  Jin Xun, Haidong Huang, Kurt W. Vogel, Dale Drueckhammer, The Importance of the Amide Bond Nearest the Thiol Group in Enzymatic Reactions of Coenzyme A, Bioorg. Chem. 2005, 33, 90-107.

 

 

) ) ) ) [RightCol] => Array ( ) ) -->

Selected Publications

1.    Zixing Zhuang, Rui Pan, Qian Zhang, Haidong Huang, Molecular Recognition of Pyrimidines by Triplex DNA Receptors. Bioorg. Med. Chem. Lett. 2015, 25, 1520-1524.

2.    Haidong Huang, Peter C. Tlatelpa. Tuning the Selectivity of Triplex DNA Receptors. Chem. Commun. 2015, 51, 5337-5339.

3.    Peter C. Tlatelpa, Haidong Huang. Stability of Pyrimidine N-glycosydic Bonds in the Presence of Lawesson’s Reagents: Revisit of 2-Thiolation of Pyrimidine Nucleosides. Tetrahedron Lett. 2014, 55, 4780-4784.

4.    Jagruti Rana, Haidong Huang, Actions of the Klenow Fragment of DNA Polymerase I and Some DNA Glycosylases on Chemically Stable Analogues of N7-methyl-2’-deoxyguanosine. Bioorg. Med. Chem. 2013, 21, 6886-6892.

5.    Qian Zhang, Yiqi Wang, Xianyang Meng, Rik Dhar, Haidong Huang, Triple-stranded DNA Containing 8-Oxo-7,8-dihydro-2’-deoxyguanosine: Implication in the Design of Selective 8-Oxo-7,8-dihydroguanine Aptamer Sensors. Anal. Chem. 2013, 85, 201-207.

6.    Sejal Patel, Jagruti Rana, Jyoti Roy, Haidong Huang, Cleavage of Pyrene-stabilized RNA Bulge Loop by Cyclohexane-1,2-diamine. Chem. Cen. J. 2012, 6:3.

7.    Jyoti Roy, Payal Chirania, Sanniv Ganguly, Haidong Huang, A DNA Aptamer Sensor for 8-Oxo-7,8-dihydroguanine. Bioorg. Med. Chem. Lett., 2012, 22, 863-867.

8.    Mayurbhai Patel, Avishek Dutta, Haidong Huang, A Selective Adenosine Sensor Derived from a Triplex DNA Aptamer. Anal. Bioanal. Chem. 2011, 400, 3035-3040.

9.    Haidong Huang, Shuhei Imoto, Marc M. Greenberg, The Mutagenicity of Thymine Glycol in E. coli Is Increased When It Is Part of a Tandem Lesion. Biochemistry 2009, 48, 7833-7841.

10.  Haidong Huang, James T. Stivers, Marc M. Greenberg, Competitive Inhibition of Uracil DNA Glycosylase by a Modified Nucleotide Whose Triphosphate Is a Substrate for DNA Polymerase. J. Am. Chem. Soc. 2009, 131, 1344-1345.

11.  Haidong Huang, Marc M. Greenberg, Hydrogen Bonding Contributes to the Selectivity of Nucleotide Incorporation Opposite an Oxidized Abasic Lesion by DNA Polymerases. J. Am. Chem. Soc. 2008, 130, 6080-6081.

12.  Haidong Huang, Marc M. Greenberg, Synthesis and Analysis of Oligonucleotides Containing Abasic Site Analogues. J. Org. Chem. 2008, 73, 2695-2703.

13.  Haidong Huang, Dale G. Drueckhammer, A Modular Molecular Tweezer Designed Using CAVEAT, Chem. Commun. 2006, 2995-2997.

14.  Haidong Huang, Dale G. Drueckhammer, A Computer-Designed Macrocyclic Zinc Receptor, Chem. Commun. 2005, 5196-5198.

15.  Jin Xun, Haidong Huang, Kurt W. Vogel, Dale Drueckhammer, The Importance of the Amide Bond Nearest the Thiol Group in Enzymatic Reactions of Coenzyme A, Bioorg. Chem. 2005, 33, 90-107.