You are in the College of Science and Liberal ArtsCollege of Science and Liberal Arts

Department of Chemistry and Environmental Science

Huang, Haidong

Contact Info
Title:
Email: haidong.huang@njit.edu
Office: 370 Tiernan Hall
Phone: 973-596-3576
Dept: Chemistry and Environmental Science
Webpage:

Academic Interests: bioorganic chemistry, nucleotides

About Me

Education

  • Ph.D 2006, State University of New York at Stony Brook
  • BS 2000, Peking University, China

Courses I Teach

RESEARCH & INDEP STUDY I
MASTERS PROJECT
DOCTORAL DISSERTATION

Research Interests

  • Using artificial receptors to detect damaged DNA bases.
  • Using synthetic analogues to study mutagenic effect of DNA alkylation.
  • Artificial ribonucleases.

Selected Publications

1.      Zhang, Q., Wang, Y., Meng, X., Dhar, R. Huang, H. (2013) Triple-stranded DNA containing 8-oxo-7,8-dihydro-2’-deoxyguanosine: Implication in the design of selective 8-oxo-7,8-dihydroguanine aptamer sensors. Anal. Chem. 85, 201-207.

2.      Roy, J., Chirania, P., Ganguly, S., Huang, H. (2012) A DNA aptamer sensor for 8-oxo-7,8-dihydroguanine. Bioorg. Med. Chem. Lett., 22, 863-867.

3.      Patel, S., Rana, J., Roy, J., Huang, H. (2012) Cleavage of pyrene-stabilized RNA bulge loops by cyclohexane-1,2-diamine. Chem. Cent. J., 6:3.

4.      Patel, M., Dutta, A., Huang, H. (2011) A selective adenosine sensor derived from a triplex DNA aptamer. Anal. Bioanal. Chem., 400, 3035-3040. 

5.      Huang, H., Imoto, S., Greenberg, M. M. (2009) The mutagenicity of thymidine glycol in Escherichia coli is increased when it is part of a tandem lesion. Biochemistry, 48, 7833-7841.

6.      Huang, H., Stivers, J. T.; Greenberg, M. M. (2009) Competitive inhibition of uracil DNA glycosylase by a modified nucleotide whose triphosphate is a substrate for DNA polymerase. J. Am. Chem. Soc., 131, 1344-1345.

7.      Huang, H., Greenberg, M. M. (2008) Hydrogen bonding contributes to the selectivity of nucleotide incorporation opposite an oxidized abasic lesion by DNA polymerases. J. Am. Chem. Soc., 130, 6080-6081.

8.      Huang, H., Greenberg, M. M. (2008) Synthesis and analysis of oligonucleotides containing abasic site analogues. J. Org. Chem., 73, 2695-2703.

9.      Huang, H., Drueckhammer, D. G. (2006) A modular molecular tweezer designed using CAVEAT. Chem. Commun., 2995-2997.

10.  Huang, H., Drueckhammer, D. G. (2005) A computer-designed macrocyclic zinc receptor. Chem. Commun., 5196-5198.